What other cofactors or cosubstrates does the pyruvate dehydrogenase complex require to function?

Answers

Answer 1

Answer:

Pyruvate dehydrogenase (PDH) is a very high molecular weight mitochondrial multienzyme complex.It includes three types of enzymes that need the participation of five coenzymes to develop their activity, three of them catalytic cofactors (TPP, lipoamide, FAD) and two stoichiometric (NAD and CoA). Two enzymes involved in regulating its activity are also part of the enzyme complex.

Explanation:

PDH is a multienzyme complex formed by multiple copies of three catalytic proteins (E1, E2 and E3) and other structural and regulatory (phosphatase, kinase). It requires, in turn, different coenzymes (thiamine, lipoic acid) for its proper functioning. Given its enormous importance at a key point in energy production, it is highly regulated. E1 depends on thiamine pyrophosphate and catalyzes 2 stages: 1) decarboxylation of pyruvate, forming a hydroxyethyl-thiamine-diphosphate intermediate; 2) reductive acetylation of the lipoyl group, covalently linked (amide) to E2. E2 catalyzes the transfer of the acetyl group to CoA (3). E3 regenerates the oxidized lipoyl, transferring its electrons first to FAD and then to NAD.


Related Questions

A HOX gene called Pax6 is required for developing light sensing eyes (or eye-like structures) in a range of taxa including Cnidaria, Mollusca, Arthropoda, and Chordata. Humans (Chordata) and squid (Mollusca) have complex eyes with many shared features, like a lens, that are NOT found in other taxa that have eyes or eye-like structures. Which of the following statements is TRUE?A. If human eyes and squid eyes are analogous, then the Pax6 gene in humans and squid will be nearly identical.B. If human eyes and squid eyes are analogous, then their shared common ancestor would also have complex eyes.C. If human eyes and squid eyes are homologous, then the Pax6 gene in humans and squid will be nearly identical.D. If human eyes and squid eyes are homologous, then they have independent evolutionary origins.

Answers

Answer:

hgs do lm jb each l ok bc Z ok but we b

tell me

Which protist is characterized by a pseudopod?​

Answers

Answer:

if you're taking the unit test the answer is sarcodine

Explanation:

In tomatoes, the following hypothetical pathway gives rise to different fruit colors. Y gene R gene Precursor substrate Intermediate substrate Product and lacks color and fruit is and fruit is yellow fruit is red green from chlorophyll Mutations in the genes for both of the enzymes produce lack-of-function, recessive alleles. What would be the expected genotypic and phenotypic segregation ratios if you self-fertilize a RrYy individual

Answers

Answer:

Explanation:

From the information given:

The analysis of the hypothetical pathway gives:

                         Y gene                                  R gene

Green fruit            →         Yellow fruit               →           Red fruit.

If RrYy undergoes self-fertilization, the expected genotypic and phenotypic segregation is:

RrYy × RrYy

The progenitors to undergo the segregation are as follows:

                 RY            Ry            rY                 ry

RY             RRYY      RRYy         RrYY            RrYy

                (red)           (red)        (red)            (red)

Ry             RRYy        RRyy         RrYy           Rryy

                (red)         (green)       (red)           (green)

rY             RrYY           RrYy         rrYY            rrYy

               (red)             (red)        (yellow)      (yellow)

ry              RrYy         Rryy            rrYy             rryy

                (red)          (green)        (yellow)      (green)

Thus; the expected phenotypic ratio is:

= 9(red)  : 3(yellow) : 4(green)

The expected phenotypic ratio is:

= 1(RRYY): 2(RRYy): 2(RrYY): 4(RrYy): 1(RRyy): 2(Rryy): 1(rrYY): 2(rrYy): 1(rryy)

What is the main factor that causes the bedrock to weather at different rates?

Answers

Answer:

more resistant

Explanation:

bedrock is resistant to weathering and erosion

The practice of science can answer only scientific questions. And scientific
questions guide the design of investigations. What is usually true of the
possible answers to a scientific question?
A. They can lead to additional questions about the phenomenon.
B. They overturn an established scientific theory.
OC. They lead to the discovery of.a new scientfic law.
OD. They remove the need for further scientific inquiry.

Answers

Answer:

A scientific question is usually guided by a hypothesis which can lead to additional questing about the phenomenon (A).

Please rate positive and give brainlist for future help!

Explanation:

A scientific question can lead to additional questions about the phenomenon. The correct option is A.

What is a scientific question?

A scientific question is one that could result in a hypothesis and assist us in determining the cause of an observation.

A good scientific hypothesis must be verifiable and quantifiable. You can perform an experiment to find the solution. eschews all opinions of any type.

A scientific question is testable, to put it simply. A testable inquiry is one that focuses on things, creatures, or occurrences in our immediate environment.

By examining quantifiable data and supporting evidence, it can be resolved by experimentation, observation, or other data collection methods.

A scientific query can spawn more inquiries into the phenomenon.

Thus, the correct option is A.

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The energy value listed for foods refers to the
a. total amount of chemical energy in the food
b. amount of energy available as fuel for the body
C. total nutritional value of the food
d
amount of carbohydrates

Answers

Answer:

b. amount of energy available as fuel for the body

Answer: B

amount of energy available as fuel for the food

Explanation:

EDGE 2021

Cells in many-celled organisms...

A. All look the same
b. All have the same structure
c. are often quite different from each other
d. are the same size in every part of the organism

Answers

Answer:

c. are often quite different from each other

Explanation:

Multicellular organisms - composed of several different cells: Cells in these organisms differ in relation to the function to be performed.

The cells in these organisms are growing, developing, and reproducing.

The cells differ in shape, size, and role they have in the organism.

In the group of multicellular organisms are animals (Animalia), plants (Plantae), and fungi (Fungi).

Cells in many-celled organisms are often quite different from each other. Therefore option C is correct.

In many-celled organisms, such as animals and plants, cells can be specialized for specific functions, leading to their differentiation and diversification.

Different types of cells have distinct structures and perform specific tasks within the organism.

For example, nerve cells (neurons) are specialized for transmitting electrical signals, muscle cells for contraction, and blood cells for carrying oxygen and nutrients.

This specialization allows for efficient division of labor, where each cell type contributes to the overall functioning of the organism.

The diversity of cell types and their functions is a fundamental aspect of the complex organization and functioning of multicellular organisms, contributing to their overall biological complexity and adaptability.

Therefore option C are often quite different from each other is correct.

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do all animal cells have same genetic content(DNA)?!... if so why are the cells grouped into tissues?​

Answers

Answer:

Becasue there are different type of cells within the body that function different ways.

Explanation:

Which of these statements is true of stable atoms?

a. They have an equal number of protons and neutrons.

b. They have an equal number of electrons and protons.

c. They have an equal number of neutrons and electrons.

d. They are constantly losing or gaining particles.​

Answers

Answer:

b they have equal number of protons and electrons

Explanation:

d is the ans vbbv. u bb

vu

In pea plants the allele for tall plants in dominant to the allele for short plants, and the allele for purple flower colour is dominant to the allele for white flower colour. What is the genotype of a short plant produced from a cross between a true-breeding purple flowered pea plant and a true-breeding white flowered pea plant? *
1.TTPP
2.ttpp
3.ttPP
4.ttPp
5.TtPp

Answers

Answer:

The correct answer is - 4. ttPp

Explanation:

Given - tall is dominant over short pea plant

let assume T is dominant and t is short which is recessive

Similarly, P for dominant purple flower and p for white flower

The offspring has a short plant which means it has both t allele or recessive allele for the height of a plant by the cross of a true-breeding purple and true-breeding white:

    P   P

p   Pp Pp

p   Pp Pp

This means the offspring would have a heterozygous case for the genotype of the flower of the pea plant

Thus, the correct answer is ttPp

ASAP PLEASE

Which of the following statements is true?

A) Thymine pairing with adenine is a DNA mutation.

B) Tt and tt plants have the same genotype.

C) Bb and BB flowers have the same phenotype.

D) Intelligence is determined by a single genes.

Answers

Answer:

B.

Explanation:

Yes, Tt and tt have the same geneotype.

Two geneotypes can result in the same phenotype.

        ✧・゚: *✧・゚:*  Answer:  *:・゚✧*:・゚✧       ✅ B) Tt and tt plants have the same genotype.

 

~ ₕₒₚₑ ₜₕᵢₛ ₕₑₗₚₛ! :₎ ♡           ~

How can the idea that different minerals are formed in different environments provide evidence for energy and matter cycling?
Please do not copy and put in your own words.

Answers

Answer:

Various environment have unique environmental properties that make up matter.

Explanation:

Life on earth follows a cyclic nature, the energy that is received from the sun is recycled back to space. Similarly, various environments such as terrestrial, aquatic all are possessed different energy and have matter circulating through the ecosystem. Different factors like climate vegetation and other organisms help in the formation of soil which constitutes certain minerals. Similarly, the different region has diverse geologic settings that lead to the formation of diverse minerals such as limestone, sandstone, and resources like coal, petroleum, etc.

How would you classify the most recent historical examples of STEM

Answers

Answer:

science discovries because it is

Explanation:

12 less then m is no less than 132

Answers

Answer:

144

Explanation:

acc. to the question :

m - 12 = 132

adding 12 to both the sides :

m = 132 + 12

= 144

Answer:

m=144...........

Explanation:

12+132=144

how do dirty wells and ponds harm us?

Answers

Organic chemicals can enter the grond water and contaminate private wells through waste disposal etc.

What likely occurred in the nebula as a result of these changes?

Answers

Answer:

In the solar nebula, this likely grew out of inhomogeneties in the initial contraction. ... After this, the nebula became more transparent to solar radiation, and the nebula would have begun to cool. This would have allowed new compounds to form, growing as dust grains by condensation. Explanation:

give me brainly:) pls i only got two brainly :/

What planet is this? I'll give brainliest!

Answers

mercury please mark me brainliest. have a great day and good luck with school

V
Which list places different units of matter in the correct sequence from
largest to smallest?
O A. Human body, organs, molecules, atoms, neutrons
B. Human body, molecules, organs, atoms, neutrons
C. Human body, atoms, organs, molecules, neutrons
D. Human body, organs, atoms, molecules, neutrons

Answers

Answer: A

Explanation:

A list that places different units of matter in the correct sequence from largest to smallest is as follows:

The human body, organs, molecules, atoms, and neutrons.

Thus, the correct option for this question is A.

What is Matter?

A matter may be characterized as any substance that significantly possesses mass and takes up space by having volume. It is anything that physically takes up space and can be weighed. In other words, the matter has volume and mass. There are many different substances, or types of matter, in the universe.

The human body is a structure that consists of numerous body systems in order to perform multiple functions for their survival. These body systems may include various organs. Molecules are composed of atoms that have three subatomic particles like electrons, protons, and neutrons.

Therefore, the Human body, organs, molecules, atoms, and neutrons is on the list that places different units of matter in the correct sequence from largest to smallest. Thus, the correct option for this question is A.

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Name any four animals which take careof their babies​

Answers

Answer:

Peguins, Elephants, Orangutans, Octopi

Explanation:

Hope this helps :)

-Octopi litterally starve themselves for their children when nesscary it's cute-

-For the first full month of life, baby orangutans never let go of their mother-

-All the female adults in a elephant herd take turns watching the baby-

-Dad emperor peguins take care of their children for two months while the momma is out at sea replenshing herself, in both egg and baby form-

which organelles can be found in both plant and animal cells

Answers

Answer:

1. Cytoplasm

2. Plasma membrane

3. Nucleus

4. Mitochondria

Consider the following population:

Blood Type A B AB O
Number of individuals 533 84 67 316

What is the frequency of the IB allele in this population?

Answers

Answer:

0.079

Explanation:

Using Hardy Weinberg equilibrium for  blood group;

p² + 2pq + q² + 2pr + r² + 2qr = 1

where;

p = allele frequency for A

q =  allele frequency for B

r =  allele frequency for O

N(p² + 2pr) = the number of allele for type A people

N(q² + 2qr) = the number of allele for type B people

N(2pq) = the number of allele for AB people

N(r²) = the number of allele for O people

N(r²) = 316

r² = 316/1000

r² = 0.316

r = [tex]\sqrt{0.316[/tex]

r =  0.56

To find the frequency of the [tex]I^B[/tex] allele;

N(q² + 2qr) = 84

q² + 2qr = 84/1000

q² + 2qr = 0.084

where;

r = 0.56

q² + 2q(0.56) = 0.084

q² + 1.12q = 0.084

q² + 1.12q - 0.084 = 0

Using the quadratic formula:

[tex]=\dfrac{-b \pm \sqrt{b^2-4ac}}{2a}[/tex]

where;

a = 1, b = 1.12, c = -0.084

[tex]=\dfrac{-(1.12) \pm \sqrt{(1.12)^2-4(1)(-0.084)}}{2\times 1}[/tex]

[tex]=\dfrac{-(1.12) \pm \sqrt{1.2544-(-0.336)}}{2}[/tex]

[tex]=\dfrac{-(1.12) \pm \sqrt{1.5904}}{2}[/tex]

[tex]=\dfrac{-(1.12) \pm 1.261}{2}[/tex]

[tex]=\dfrac{-(1.12) + 1.261}{2} \ \ OR \ \ \dfrac{-(1.12) - 1.261}{2}[/tex]

[tex]=\dfrac{0.141}{2} \ \ OR \ \ \dfrac{-2.381}{2}[/tex]

[tex]\simeq 0.079 \ \ OR \ \ -1.1905[/tex]

Since our value can be negative; then the frequency of the  [tex]I^B[/tex] allele in this population is 0.079.

Which pair of soil compounds does manure management balance?
nitrogen and ammonia
nitrogen and phosphorous
ammonia and phosphorous
potassium and phosphorous

Answers

Answer:

I think nitrogen and phosphorus

Which animal had to eat the most frequently in order to maintain its energy
level?
A. Rattlesnake
B. Small fish
C. Hummingbird
O D. Kangaroo rat

Answers

Answer:D

Explanation:

Answer:

C. Hummingbird Have a great night or day

Explanation:

100% correct A P 3 X I just did the assessment i got all the answers right :)

What is the cause of the differences in the offspring?

Answers

Answer:

animals with different species interbreed to produce a different and infertile offspring

Proteins are created by the
Golgi body
mitochondria
rough ER
smooth ER

Answers

Proteins are created by Ribosomes

Describe three roles of lipids

Answers

Answer:

-storing energy

-chemical messengers

-structure

Explanation:

-chemical messengers , structure & storing energy

During most of the cell's life, the chromosomes will be in the form of
O Chromatin
O Sister chromatids
O Homologous chromosomes
O Tetrads

Answers

During most of a cells life the chromosomes would be in a form of A. Chromatin

During most of the cell's life, the chromosomes will be in the form of - Chromatin.

The DNA wrapped around histones is further organized into higher-order structures that give a chromosome its shape.

This form of the chromosome is called chromatin and it is the form chromosome most of the life of the cell.In this form chromatin is decondensed, meaning that it exists in long, thin strings form.It is found in the interphase most of the cell's life.

Thus, During most of the cell's life, the chromosomes will be in the form of - Chromatin.

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Which is a viable way to combat the effects of drought on the population of Sub-Saharan Africa?
A)
seeding the clouds
B)
increasing irrigation
C. increasing livestock
D)
planting many trees
H

Answers

Answer:

i am not that smart but think it's C

Explanation:

The chemical reaction of water and carbon dioxide to form sugar is ... reaction in terms of molecules.

Answers


20 words do be annoying

In one or two sentences, explain how the chemical equation for cellular respiration shows that plants cycle matter. Include the numbers of molecules and atoms involved to support your explanation.

Answers

Carbon dioxide + Water Glucose (sugar) + Oxygen CO2 + H2O C6H12O6 + 6O2 Cellular respiration or aerobic respiration is a series of chemical reactions which begin with the reactants of sugar in the presence of oxygen to produce carbon dioxide and water as waste products.

Glucose + Oxygen ------> ATP + Carbon dioxide + Water

C6H12O6 + 6O2 ----------> 36ATP + CO2 + H2O

The chemical equation for cellular respiration shows that plants cycle matter because oxygen and glucose that is produced by the plants is used by the human body for the generation of energy in the form of ATP molecules, water and carbondioxide gas.

This carbondioxide gas is released by animals which is used by the plants in order to make their own food during the process of photosynthesis so we can conclude that the chemical equation for cellular respiration shows that the plants cycle matter.

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