With the use of site-directed mutagenesis, hemoglobin has been prepared in which the proximal histidine residues in both alpha and the beta subunits have been replaced by glycine. The imidazole ring from the histidine residue can be replaced by adding free imidazole in solution. Would you expect this modified Hb with free imidazole to exhibit oxygen binding? Why or why not?

Answers

Answer 1

Answer:

The modified hemoglobin with free imidazole cannot be expected to show cooperativity in oxygen binding. The movement of iron ion takes place up in the plane of heme when binding of one subunit of hemoglobin takes place with oxygen. One of the iron's and oxygen's axial ligands comprise the proximal histidine's imidazole ring.  

With the movement of iron into the hemoglobin ring, the pulling of proximal histidine takes place along with it. Therefore, when binding of oxygen takes place with one subunit, a modification also takes place in the intersubunit associations, this also comprises displacement of the alpha helix. This phenomenon plays an essential role in modifying the hemoglobin's tensed state to the relaxed state. The withdrawal or mutation of the imidazole ring from the histidine residue does not further permit the cooperative binding as it is not associated physically with the alpha-helix.  


Related Questions

Which is an example of foraging as a benefit of social behavior?

Answers

Answer:

kinda like foraging a signature

Explanation: if I'm wrong go randonauting

Photosynthesis is an example of what kind of reaction

Answers

Answer:

a complex reaction

Explanation:

light sun and carbon dioxide are created

Answer:

Anabolic or endothermic

Explanation:

Photosynthesis is an example of anabolic reaction because we build complex carbs from relative simple building material and it is also an endothermic reaction because we need the energy from sun to start the reactions in photosynthesis.

Both are correct, depends on what you options you are given or what you've been taught.

why Sexually transmitted Infection are more readily passed from male to female

Answers

Answer:

STDs are more readily passed male to female as opposed to female to male because the male is as a requisite to sex sharing his bodily fluid (semen) directly with her. That means that any fluids are likely to enter into an internal cavity of hers.

On the other hand, any bodily fluids she releases, which are not requisite to sex, are likely to stay on the outside of the man's body because they will just go onto the skin of his genital area.


What is the approximate carrying capacity of the
population?
In which year, did the population reach the
carrying capacity?
About how many years did it stay at carrying
capacity?

Answers

Answer:

250 individuals

year 3

4 years

Explanation:

Answer:250

year 3

4 years

Explanation:

Which element is a metaloid

Answers

Answer:

Elements that are the border line of metals and non-metals.some elements near the stepped line have mixed properties of metals and non-metals these elements are called metalloid e.g. Silicon and Germanium

Explanation:

I hope this will help you:)

Both DNA and RNA are synthesized by covalently linking a nucleoside triphosphate to the previous nucleotide, constantly adding to a growing chain. In the case of DNA, the new strand becomes part of a stable helix. The two strands are complementary in sequence and antiparallel in directionality. What is the principal force that holds these two strands together

Answers

Answer:

The correct answer is - hydrogen bond.

Explanation:

Hydrogen bonding is very essential for life on earth. DNA has a double-helix structure that means it has two distinct strands in its structure and hydrogen bonds hold together the nitrogen base pairs in the middle. In absence of hydrogen bonds, DNA would have to exist as a different structure. The principal force or bonds between those two strands are Hydrogen bonds between the nitrogen bases.  Adenine always makes a hydrogen bond with Thymine whereas Guanine always binds with cytosine.

Thus, the correct answer is - hydrogen bond.

4. What about each person's chromosomes make them unique?

Answers

Answer:The DNA in each persons chromosomes makes them unique

Explanation: Representing segments of the genome that have been passed down from generation to generation, occasionally being shuffled amongst chromosome pairs. This shuffling has helped drive evolution through time, and ultimately has helped write your genome and the story of you.

studied the role of RNA in protein synthesis, specifically in the bacteria E. coli.

Answers

The question is incomplete. The correct question is as following:

__________ studied the role of RNA in protein synthesis, specifically in the bacteria E. coli.

Answer:

Marshall Nirenberg and Heinrich Matthaei

Explanation:

Marshall Nirenberg and Heinrich Matthaei are two biochemist and geneticist who studied the functional importance of RNA in the process of translation (protein synthesis) experimentally in E.Coli.

Nirenberg and Matthaei discovered the first codon out of 64 codons present in RNA and they successfully performed translation (protein synthesis) in E.coli in a test tube. They decoded the first codon UUU (phenylalanine) by using synthetic RNA having only uracil nucleotides in a E.Coli and later they decoded further codons.

So, the correct answer is  Marshall Nirenberg and Heinrich Matthaei.

Explain why detritivores, decomposers and omnivores are not assigned trophic level​

Answers

Answer:

They can be found in several trophic levels, as they are related with several trophic level, hence, they cannot be placed on a specific trophic level.

Explanation:

A trophic level is a specific position occupied by a group of organisms on a good chain in relation to their nutrition.

Dentrivores feed on the waste of other organisms and cannot be really placed on a specific trophic level, likewise decomposers, of which they feed and decompose the body of organisms.

Omnivores feed on both plants and animals, which includes producers and consumers. Placing omnivores on a specific trophic level would not be really straightforward also.

What is the correct order of processes in the accretion of planetesimals?
1)Masses of matter form around dust grain, masses of matter collide, and atoms and molecules are added to dust grain.
2)Masses of matter collide, masses of matter form around dust grain, and atoms and molecules are added to dust grain.
3)Atoms and molecules are added to dust grain, masses of matter form around dust grain, and masses of matter collide.
4)Masses of matter collide, atoms and molecules are added to dust grain, and masses of matter form around dust grain.

Answers

Answer:

The correct option is 3. Atoms and molecules are added to dust grain, masses of matter form around dust grain, and masses of matter collide.  

Explanation:

Two theories explain how planets get formed. One of them is The gravitational instability, and the other one is the Planetesimal Hypothesis.

The planetesimal hypothesis says that a planet formation is a process in which dust particles and gas collide and get stick together in a process known as coagulation. This makes place to grains production. These grains enhance their sizes up to a point in which they form bodies big enough to be called planetesimals. When planetesimals are formed, they start a gravitative interaction with other planetesimals of different sizes, and by collision, they form bigger planetesimals that accrete the smaller ones and end up forming a proto-planet. Planets and giant planets get formed by accretion of solid planetesimals. The term accretion refers to the solids agglomeration to form bigger objects, such as planets.    

Answer:

c

Explanation:

took the quiz

In which of the following ways is region b in the diagram different from region D

Answers

Answer:

The A region is - the central sulcus and D region is -  cerebellum

Explanation:

The central sulcus is a noticeable part of the brain, isolating the parietal lobe from the frontal lobe. It additionally isolates the primary somatosensory from cortex posteriorly from the primary motor cortex anteriorly. the most prominent approach to locate the central sulcus by starting the medial surface of the hemisphere.

The cerebellum plays major role in motor movements by coordinate the force of these different muscle groups and their timing to produce body movements. It is present dorsal to the pons and the medulla, to make an essential structure of the hindbrain. It lies under the occipital and temporal lobes of the cerebral cortex.


How can foreign pieces of DNA be transferred into organisms?


A) by restriction enzymes

B) by vectors

C) by carrier enzymes

D) by test crosses

Answers

Answer:

B) Vectors

Explanation:

They are also called carriers.

Which description refers to cumulus clouds?
are fluffy
form layers
are usually gray
cover most of the sky
I need help ASAP!!!

Answers

Answer:

Cumulus clouds are fluffy  

Explanation:

From Latin, cumulus refers to a group or a bunch. Cumulus clouds are isolated clouds of a horizontal base and show vertical growth or development. They might adopt some kind of cotton mountain or domes. They have well-defined outlines, and they can easily reach many sizes and thicknesses. They originate because of the presence of strong convection streams and fast elevations of warm air.

Answer:

A

Explanation:

pls help look at the above image and answer the questions thx ​ if you do not know all the questions you can answer the one you know

Answers

Answer:

1.animal diversity

2.don't no sorry

3.grass

4.rabbit

5.Tiger

6.

How would you summarize your observations on the relationship between the allele frequency in the gene pool and the frequency among the zygotes, as the number of zygotes formed increases?

Answers

Answer:

Explanation:

Gene pool consist of all the gene in an entire population while an allele frequency is how often an allele occur in the population.

Allele and gene frequency are often affected by Evolution. We have tgw micro and macroevolution. The microevolution involves the changes that occur in an allele or gene frequency from generation to generation while the macroevolution are accumulated changes that takes years to occur. Due to evolution, as new zygotes are formed some allele are lost due to selection, some are been drifted away by genetic drift , some still reoccur and new species also occur after years of accumulated changes. The greatest force of changes in gene pool as zygotes are been formed is evolution.

10. In the water cycle, liquid changes to gas by
O precipitation
O condensation
evaporation
O freezing

Answers

Answer:

evaporation

Explanation:

when the liquid heated for a long time it removes steam in form of gases

In the water cycle, liquid changes to gas by evaporation, which is in Option C. The water cycle, also known as the hydrological cycle, describes how water circulates through the Earth's ecosystems.

What is the water cycle?

The water cycle involves a series of processes that include evaporation, condensation, precipitation, and infiltration. Evaporation is the process by which water changes from a liquid state to a gaseous state, such as water vapor. This occurs when energy (in the form of heat) is absorbed by the water, causing the water molecules to move faster and break free from their bonds to form a gas. After water evaporates, it can undergo condensation, which is the process by which water vapor changes back into liquid water.

Hence, in the water cycle, liquid changes to gas by evaporation, which is Option C.

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When can
exponential growth occur in a population?

Answers

Answer:

c

Explanation:

Exponential growth is when a population increases in a given time when resources are unlimited. In regular nature, resources will eventually run out, but if they are unlimited, they can grow exponentially

Exponential growth can occur in a population when there are unlimited resources and no limiting factors such as disease, predation, or competition.

What is exponential growth?

Exponential growth refers to a phenomenon in which a population, a species, or a quantity increases at a rate that is proportional to its current size. In other words, as the population grows, the rate of growth also increases. This can lead to a rapid increase in population size over a short period of time.

Exponential growth can occur when there are favorable conditions for reproduction and survival, such as an abundance of resources and a lack of predators or diseases. This type of growth is often seen in microorganisms, such as bacteria, and in populations of animals that have no natural predators or competitors. However, exponential growth is not sustainable in the long term, as eventually resources will become scarce and the population will stabilize or decline.

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The element with an atomic number of 4 is?

Answers

Answer:

Be

Beryllium

Explanation:

number of protons = atomic number.

number of electrons = atomic number

Answer:

Beryllium

Explanation: Per Penn and Foster

what is a spinal cord

Answers

Answer:

The spinal cord is a long, thin, tubular structure.

Explanation:

The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column. It encloses the central canal of the spinal cord, which contains cerebrospinal fluid.

Answer:

it is a tissue

Explanation:

One pound of body fat stores about 3,500 food Calories of energy. How many joules
does make

Answers

One calorie has the same energy value as 4.186 joules. It takes 3,500 calories to equal one pound of body weight. The energy value per GRAM of various food components includes: Water = 0kJ (0 Cal)

The unit of energy expressed by the foods is defined by calories. One pound of fats has been known to have 3500 calories. The energy in joules is 14651 Joules.

What are calories?

Calories are defined as the unit of energy that comes from the food an organism consumes and drinks. These calories are important as they provide cellular and metabolic energy.

The calories should be in a balanced amount and not too much or too low, as it can lead to obesity and malnutrition resulting in various body diseases and disorders.

It has been known already that one pound of fats has 3,500 calories in them that provide energy. Also, it has been known that 1 calorie = 4.184 joules, so, 3500 calories = 3500 × 4.184 = 14651 joules or 14.65 Kilojoules.

Therefore, 3500 calories contain 14651 joules of energy.

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PLEASE HELP


1. When recommending solutions to decrease human impact, which location were you able to make the greatest positive impact? Please explain your selection by using data from the simulation.


2. What recommendations would you give to your local community to help to decrease the local effects of human impact on the environment? List 2 recommendations and how they will positively impact your community.


3. What recommendations would you give to the global governments to help decrease the global effects of human impact on the environment? List 2 recommendations and how they will positively impact our planet.

Answers

Answer:

Explanation:

1,The Amazon rain forest

The reforestation of the Amazon forest after logging is a significant impact of human activities,This re- population of trees ensures that the effect of logging, the human impact, is reduced to barest minimum, which reduce  air population and therefore the green house effects.

In addition, the use of recycled material which reduced contamination and therefore promote safe water is another reduction in human impact. However the preservation of the Amazon is global.And therefore its conservation of the CO2 for earth usage is important to all to prevent global warming and continuous existence of human beings through photosynthesis.,

2.

Indiscriminate  dumping and burning of refuse should be avoided- this leads to carbon emission and CO pollution.

Fertiliser applications close to lakes and rivers should be reduced.

These impacts leads to air pollution and respiratory disorders, fog which reduces visibility Therefore if open combustion is avoided this  reduces the above effects. Waste disposal should be managed by  governments, in a designated areas and not by induviduals

.Leakages of these NPK fertilizers leads to eutrophication and therefore increase in the aquatic organic matter, reduction of oxygen of the aquatic bodies and death of the fauna. Fertiliser application near aquatic bodies should be reduced,Compost and manure should be used near this areas.

3.

The use of Combustion engines should be reduced drastically as this is the main source of climate change of  global warming, air pollution and flooding. Governments should invest in the mass production of electric cars, with  the release of no pollutants to the environments.

Like wise, recycling of used paper materials will ensure continuous availability of paper, and therefore cut down incessant felling of trees for paper production.Besides, steel and other metallic materials use be used more  for furniture productions, thereby conserving  rain forests.These will preserve the global ecosystem and ensure stability.

When recommending solutions to decrease human impact, which location were you able to make the greatest positive impact? Please explain your selection by using data from the simulation.

New york, 893 - 853 = 40 which is the highest quotient.  

What recommendations would you give to your local community to help to decrease the local effects of human impact on the environment? List 2 recommendations and how they will positively impact your community.

Installing solar panels and replanting 2 trees for every tree that’s been cut down, this will help the atmosphere and deforestation.  

What recommendations would you give to the global governments to help decrease the global effects of human impact on the environment? List 2 recommendations and how they will positively impact our planet.

Constructing using only recycled materials decreases water pollution to 823 ppm and Creating more protected areas decreases air pollution to 368 ppm this will help the environment and oxygen.  

After a person recovers from the chickenpox the virus can lie dormant in the dorsal root ganglion in multiple levels of the spinal cord and cranial nerves. Later in life, the virus can be reactivated and travel within a sensory neuron to cause shingles. Do you think it is possible to get shingles more than once?

Answers

Answer:

No

Explanation:

It is scientifically impossible.

A sample of living tissue of a fish-eating bird species was found to have a specific, heavy metal concentration of 700,000 ppt (parts per trillion). What is the best inferential explanation you could make based on these data

Answers

Answer:

The best inferential explanation is that the heavy metal concentration was gotten from the build up of small amounts of heavy metal in the birds, gotten from consuming fishes from a heavy-metal -polluted water body.

Explanation:

If a sample of fish-eating bird species is found to contain such a large concentration of heavy metal, then the primary source of the heavy metal concentration in their body will be from their food source. Fish-eating birds are in most cases, solely dependent on fish for their food. Most of them do not eat any other food apart from fish, so the problem can be pin-pointed to the fishes they consume. The best inferential explanation is that the heavy metal concentration was gotten from the build up of small amounts of heavy metal in the birds, that is gotten from ingesting fishes that have ingested heavy metals in them. This can be as a result of the pollution of water bodies like streams, lakes and seas from heavy-metal-containing industrial wastes.  

why i cant use blood agar with Catalase test? ​

Answers

Catalase is the enzyme that breaks hydrogen peroxide (H2O2) into H2O and O2. ... If using colonies from a blood agar plate, be very careful not to scrape up any of the blood agar— blood cells are catalase positive and any contaminating agar could give a false positive.

Answer:

Catalase is the enzyme that breaks hydrogen peroxide (H2O2) into H2O and O2. .

Explanation:

If using colonies from a blood agar plate, be very careful not to scrape up any of the blood agar— blood cells are catalase positive and any contaminating agar could give a false positive.

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Arrange the following "sound processing events" in order, from start to finish. - Vibrations are conveyed to the endolymph inside the cochlea, causing the cochlear hair cells to bend - Sound waves cause the ear drum and middle ear bones to vibrate - Bending of the cochlear hair cells causes ion channels to open, which causes neurotransmitters to be released, which results in activation of the auditory nerve, which sends signals to the brain for processing. - Sound waves move down the auditory canal toward the ear drum

Answers

Answer:

1) Sound waves move down the auditory canal toward the eardrum

2) Sound waves cause the eardrum and middle ear bones to vibrate

3) Vibrations are conveyed to the endolymph inside the cochlea, causing the cochlear hair cells to bend

4) Bending of the cochlear hair cells causes ion channels to open, which causes neurotransmitters to be released, which results in activation of the auditory nerve, which sends signals to the brain for processing

given a container of a solution of 5% hcl all samples tested from this same bottle will have the same mass ratio of hydrogen to chlorine. this application of the law of

Answers

Answer:

The law of conservation of mass.

Explanation:

This law talks about that the mass is not lost during the reactions, but is maintained.

Answer:

ITS NOT CONVERSATION OF MASS. ITS CONSTANT COMPOSITION

Explanation:

I dii ok not under stand this please help me!

Answers

Answer:Answer:

For 1: The correct answer is Model 1, 2, and 4.

For 2: The correct answer is Option 1.

Explanation:

For 1:

An element has 3 subatomic particles: electrons (E), neutrons (N) and protons (P).

Atomic number is defined as the number of protons or number of electrons.

Atoms having same number of protons are same. From the given models, Model 1, 2 and 4 have 2 protons with different neutrons. Hence, these models belong to same element.

For 2:

A compound is defined as a substance in which two or more types of elements combine in a fixed ratio. For Example:  is a compound made out of atoms of carbon and oxygen.

Hence, the correct answer is Option 2.

Which environmental change is considered short term?

forest fire
ice age
mountain building
solar energy changes

Edunuity

Answers

Answer:

forest fires

Explanation:

An environmental change that occurs quickly and affects organisms immediately (causing behavioral adaptations).

floods, forest fires, blizzards, volcanic eruptions,

Answer: Forest fires[A]

Explanation:

got 100% on the edge2020 Unit Test

have a good day:)

What is each half of a chromosome called?

Answers

It’s called sister chromatids

Answer:

Chromatid.

Explanation:

A chromatid is half of a chromosome.

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A population of tree salamanders is highly variable in color and blends easily with the surrounding, colorful vegetation. After a factory upstream impacts their environment, several species of trees die off and only those with one color of leaf and flower are left. Within several generations, the salamander population has reduced variability in color.

Answers

Answer:

This is an example of directional selection.

Explanation:

Directional selection is a type of positive selection where the evolutionary fitness of one genotype is higher compared to the other ones, thereby favoring the selection of one particular phenotype and shifting allele frequencies towards the selected genotype. In a biological context, the directional selection increases the chances for surviving and for reproducing in those organisms that have the alleles favored by this type of selection. Thus, the directional selection produces the loss of genetic variability and leads to the fixation of the dominant alleles.

Other Questions
Read the excerpt from Part 2 of The Odyssey. We would entreat you, great Sir, have a care for the gods' courtesy; Zeus will avenge the unoffending guest.' He answered this from his brute chest, unmoved: 'You are a ninny, or else you come from the other end of nowhere, telling me, mind the gods! We Cyclopes care not a whistle for your thundering Zeus. What theme is best revealed by this conflict? It is important to use manners in new situations. It is wise to know the enemy you face. Guests should honor the traditions of their hosts. Guests should offer gifts to their hosts A customer establishes a combined margin account by purchasing $10,000 of ABC stock and selling short $10,000 of XYZ stock, depositing the Regulation T requirement. Subsequently, the market value of the ABC position increases to $20,000, while the market value of the XYZ position decreases to $5,000. If no other activity occurs in the account, the account will show a current SMA balance of Gracie was surprised and pleased to find she was pregnant. She worked as a waitress at Good Food and was aware that Groucho, her employer, had allowed employees who were ill for reasons that were not work related to take paid time off. For example, her friend Craig was off with pay for two months after suffering a mild heart attack, and her friend Bonnie was off of work for three months when she ran her personal watercraft into a dock and broke her leg. Gracie told her employer Groucho about her pregnancy. He very angrily told her that pregnancy was completely voluntary, that he was not paying her a dime when she was off work, and that she would be lucky if he even allowed her to continue working at all because she would not be as cute when she gained weight. He also said that he serves families, and he does not want the kids to ask embarrassing questions of their parents regarding Gracie's condition. Gracie was very angry and threatened to sue. Groucho told her, however, that he had business law back in 1980 and that discrimination based on pregnancy is not even covered by Title VII. The employee handbook did not address the issue.What will be the likely result if Groucho defends on the basis that customers will object to Gracie's condition?a. Groucho will only prevail on a defense of bona fide occupational qualification if he can establish that Gracie was attempting to voluntarily get pregnant. b. Groucho will only prevail on a defense of bona fide occupational qualification if he can prove that he has an established history of barring pregnant servers and that he did not single out Gracie. c.Groucho will not prevail on a defense of bona fide occupational qualification because it is available in cases involving religion and national origin only. d. If he can prove that is true, then Groucho will prevail on the defense of bona fide occupational qualification. e. Groucho will lose on a defense of bona fide occupational qualification because he will not be able to establish that only non-pregnant employees can perform as servers. What was the Red Scare? a period when people were afraid of ideas such as communism and anarchism a period when many Americans died because of World War I a period when Americans feared and distrusted German immigrants [tex]\frac{?}{5} * \frac{10}{8} =1.5\\[/tex] What number would replace the '?' A 50 Hz, four pole turbo-generator rated 100 MVA, 11 kV has an inertia constant of 8.0 MJ/MVA. (a) Find the stored energy in the rotor at synchronous speed. (b) If the mechanical input is suddenly raised to 80 MW for an electrical load of 50 MW, find rotor acceleration, neglecting mechanical and electrical losses. (c) If the acceleration calculated in part(b) is maintained for 10 cycles, find the change in torque angle and rotor speed in revolutions per minute at the end of this period. when a piece of paper is held with one face perpendicular to a uniform electric field the flux through it is 25N.m^2/c. when the paper is turned 25 degree with respect to the field the flux through it is: 1. THE PERIOD OF SHAH JAHANS REIGN WAS THE GOLDEN AGE OF THE MUGHAL ARCHITUCTURE AND WAS THE MOST PROSPEROUS AGES OF INDIAN CIVILISATION. (GIVE REASONS FOR THE SUPPORT OF YOUR ANSWER) 1. Imagine this scenario: On Thursday, after your computer breaks, you order a new computer from Amazon to be delivered on Friday, paying extra so the computer arrives in time for your big presentation to the company President. If you mess this up, you will lose your job. Unfortunately, the computer does not arrive for ten days and you lose your job. What can you sue Amazon for? What promise did Amazon breach? 2. What contract provision (promise) could Amazon agree to that would make it liable for your lost job? In Romeo and Juliet, the title characters fall in love and have many obstacles to overcome, ultimately leading to their tragic deaths. Their deaths unite the feuding families, however, making the ending both sweet and sorrowful. Write a personal narrative in which you tell a story which happened to you or someone you know, relating to the topic of love and sweet sorrow Which sentence would improve this conclusion? Why does every chemical reaction require a certain amount of activation energy? .Energy is released when the reactants begin to react.OBEnergy lost to the environment during the reaction must be replaced.O c.Forming the activated complex requires energy.ODThe products have more potential energy than the activated complex.OE.The reactants have less potential energy than the products. PLS HELP 30 PIONTS AND I HAVE NO IDEA HOW TO DO IT SO MOST EXPLANATORY GETS BRAINLIEST What guidelines will you develop for supervisors to successfully respond to employee questions about unionization? What can your supervisors say or do that is legally permissible in this situation? Question 4 of 102 PointsWhich factor helps determine the fertility rate of a group of people?O A. Death rateB. EducationO c. Consumption rateD. FarmlandSUBMIT You are entering an expressway, and are in the acceleration lane. You should speed up toA: A speed slightly slower than traffic in the right lane of the expressway,B: The same speed as the traffic in the right lane of the expressway,C: The speed that allows you to safely move into a gap in traffic when you reach the merging area. The coldest layer of Earths atmosphere is the __________. a. troposphere c. mesosphere b. stratosphere d. thermosphere What does a platform committee do? A. recruits party members B. develops policy statements What is the value of p? Select the correct numbers. Identify the numbers that are located below -3.5 on a vertical number line. 3 -0.3 -1.5 -5.3 0.3 5.3 -2.5 -6.5